A notion of resource‐bounded Baire category is developed for the classPC[0,1]of all polynomial‐time computable real‐valued functions on the unit interval. The meager subsets ofPC[0,1]are characterized in terms of resource‐bounded Banach‐Mazur games. This characterization is used to prove that, in the sense of Baire category, almost every function inPC[0,1]is nowhere differentiable. This is a complexity‐theoretic extension of the analogous classical result that Banach proved for the classC[0, 1] in 1931. (© 2004 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim).

Studien zur Wissenschaftsgeschichte und Wissenschaftssystematik im 19. Jahrhundert Josef M. Werle. Drittes Kapitel Argumente zugunsten der Zukunft der Philosophie II: Wissenschaftsgeschichtliche und wissenschaftssystematische ...

The question of whether homeopathy is a science is currently discussed almost exclusively against the background of the modern concept of natural science. This approach, however, fails to notice that homeopathy—in terms of history of science—rests on different roots that can essentially be traced back to two most influential traditions of science: on the one hand, principles and notions of Aristotelism which determined 2,000 years of Western history of science and, on the other hand, the modern concept of natural science (...) that has been dominating the history of medicine for less than 200 years. While Aristotle’s “science of the living” still included ontologic and teleologic dimensions for the sake of comprehending nature in a uniform way, the interest of modern natural science was reduced to functional and causal explanations of all phenomena for the purpose of commanding nature. In order to prevent further ecological catastrophes as well as to regain lost dimensions of our lives, the one-sidedness and theory-loadedness of our modern natural–scientific view of life should henceforth be counterbalanced by lifeworld–practical Aristotelic categories. In this way, the ground would be ready to conceive the scientific character of homeopathy—in a broader, Aristotelian sense. (shrink)

A new axiomatic treatment of equilibrium thermodynamics—thermostatics—is presented. The equilibrium states of a thermal system are assumed to be represented by a differentiable manifold of dimensionn + 1 (n finite). The empirical temperature is defined by the notion of thermal equilibrium. Empirical entropy is shown to exist for all systems with the property that the total work delivered along closed adiabats is zero. Absolute entropy and temperature follow from the additivity of heat and energy for two separate systems in thermal (...) equilibrium considered as a whole. The absolute temperature is defined up to a multiplicative constant. The exterior differentiable calculus of Cartan is introduced and in a subsequent paper its use for the derivation of standard results in thermostatics will be explained. (shrink)

The mammary gland is a skin gland unique to the class Mammalia. Despite a growing molecular and histological understanding of the development and physiology of the mammary gland, its functional and morphological origins have remained speculative. Numerous theories on the origin of the mammary gland and lactation exist. The purpose of the mammary gland is to provide the newborn with copious amounts of milk, a unique body fluid that has a dual role of nutrition and immunological protection. Interestingly, antimicrobial enzymes, (...) such as xanthine oxidoreductase or lysozyme, are directly involved in the evolution of the nutritional aspect of milk. We outline that xanthine oxidoreductase evolved a dual role in the mammary gland and hence provide new evidence supporting the hypothesis that the nutritional function of the milk evolved subsequent to its protective function. Therefore, we postulate that the mammary gland evolved from the innate immune system. In addition, we suggest that lactation partly evolved as an inflammatory response to tissue damage and infection, and discuss the observation that the two signaling pathways, NF‐kB and Jak/Stat, play central roles in inflammation as well as in lactation. BioEssays 28: 606–616, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

This paper presents a new foundation of equilibrium thermodynamics based on certain ideas of T. Ehrenfest. The main result is the proof for the existence of entropy as a consequence of the conservation of energy for conservative thermal systems.

Animals are hand-raised in a variety of contexts, including experimental research. This has been criticized frequently as producing animals with species-untypical behaviour. Here we compare life histories of 330 hand-raised and 631 gooseraised Greylag geese from a free-flying flock to determine whether hand-raising affected life history, reproductive variables and behaviour. We found little differences in life histories or reproductive variables of hand-raised and goose-raised geese. However, hand-raised females had lower life expectancies than goose-raised ones, mainly due to predation during breeding. (...) Hand-raised geese were stressed significantly less during social, handling and predator stress, were attacked less by conspecifics and were less vigilant than goose-raised geese. We conclude that hand-raising resulted in geese with species-typical life histories but reduced stress responses. This makes hand-raised geese cooperative partners for research, but also more vulnerable when exposed to predators. Keywords: hand-raising; greylag goose; Anser anser; life-history; reproductive success; stress. (shrink)

Whilst the role of Maturation or M‐phase Promoting Factor (MPF) as a universal M‐phase regulator is well documented, much less attention has been paid to its role in nuclear transplantation experiments and especially to its influence upon remodelling of transplanted nuclei. There is currently wide acceptance that successful nuclear transplantation using differentiated nuclei is possible only in a cytoplasmic environment that is capable of inducing rapid nuclear de‐differentiation to a pronuclear‐like form. In this review our purpose is firstly, to outline (...) the conditions under which such remodelling can be induced, and secondly, to extend the debate to include a consideration of whether complete nuclear remodelling is an absolute necessity for clonal development. (shrink)

This article responds to the review of Hemphill and Lillevik, “The Global Economic Manifesto: A Retrospective.” It aims to contribute to the worldwide discussion of global accepted norms and values of corporate behavior by addressing universal ethical principles and implementation strategies. A focus is set on the means of specifying values to serve the action orientation of an organization and its management. Since external normative expectations rise in context of the upcoming Post-2015 Development Agenda, corporate responses need to take local (...) specifics as well as international accepted norms into account. Therefore, a distinctive implementation design is outlined. Key strategic steps contain elements such as awareness of common values, differing consequences due to cultural environments and economic conditions, integration of practical experience to gain impact-related insights, and fostering global leadership education. Consequently, corporate value management approaches and Post-2015 Sustainable Development Agenda are connected through universal values. (shrink)

The present collection deals with philosophical thinking at the medieval university from the threefold perspective of Institution and Career, Organizational Forms and Literary Genres, and School Formation and School Conflict.

Das vorliegende Buch ist bereits der dreizehnte Band der Reihe Roman Imperial Biographies. Sein Verfasser, der an der Boise State University (Idaho) lehrende Althistoriker Charles Matson Odahl (O.), ist seit den späten 70er Jahren durch eine Reihe einschlägiger Publikationen zu Konstantin und der Spätantike hervorgetreten.

Let X be an infinite internal set in an ω1-saturated nonstandard universe. Then for any coloring of [X] k , such that the equivalence E of having the same color is countably determined and there is no infinite internal subset of [X] k with all its elements of different colors (i.e., E is condensating on X), there exists an infinite internal set Z⊆X such that all the sets in [Z] k have the same color. This Ramsey-type result is obtained as (...) a consequence of a more general one, asserting the existence of infinite internal Q-homogeneous sets for certain Q ⊆ [[X] k ] m , with arbitrary standard k≥ 1, m≥ 2. In the course of the proof certain minimal condensating countably determined sets will be described. (shrink)

The litmus test for the development of a metarepresentational Theory of Mind is the false belief task in which children have to represent how another agent misrepresents the world. Children typically start mastering this task around age four. Recently, however, a puzzling finding has emerged: Once children master the FB task, they begin to fail true belief control tasks. Pragmatic accounts assume that the TB task is pragmatically confusing because it poses a trivial academic test question about a rational agent’s (...) perspective; and we do not normally engage in such discourse about subjective mental perspectives unless there is at least the possibility of error or deviance. The lack of such an obvious possibility in the TB task implicates that there might be some hidden perspective difference and thus makes the task confusing. In the present study, we test the pragmatic account by administering to 3- to 6-year-olds TB and FB tasks and structurally analogous true and false sign tasks. The belief and sign tasks are matched in terms of representational and metarepresentational complexity; the crucial difference is that TS tasks do not implicate an alternative non-mental perspective and should thus be less pragmatically confusing than TB tasks. The results show parallel and correlated development in FB and FS tasks, replicate the puzzling performance pattern in TB tasks, but show no trace of this in TS tasks. Taken together, these results speak in favor of the pragmatic performance account. (shrink)

Die Bildung des Geistes führt über ontogenetische Lernprozesse, mit denen Individuen Schlüsselfunktionen zum sozialen Einstieg in die menschliche Kultur erwerben. So etwa das wesensähnliche Verstehen anderer und das Deuten ihrer Absichten. Vor dem Hintergrund der theoretischen Philosophie von Kant versucht sich der vorliegende Beitrag über die Verknüpfung der Philosophischen Anthropologie von H. Plessner mit der Genetischen Epistemologie von J. Piaget Zugang zu dem von M. Tomasello eröffneten, evolutionsgeschichtlichen Problemfeld der Spezifikation menschlichen Verhaltens zu verschaffen.

This multidisciplinary collection explores three key concepts underpinning psychiatry -- explanation, phenomenology, and nosology -- and their continuing relevance in an age of neuroimaging and genetic analysis. An introduction by Kenneth S. Kendler lays out the philosophical grounding of psychiatric practice. The first section addresses the concept of explanation, from the difficulties in describing complex behavior to the categorization of psychological and biological causality. In the second section, contributors discuss experience, including the complex and vexing issue of how self-agency and (...) free will affect mental health. The third and final section examines the organizational difficulties in psychiatric nosology and the instability of the existing diagnostic system. Each chapter has both an introduction by the editors and a concluding comment by another of the book's contributors. Contributors: John Campbell, Ph.D.; Thomas Fuchs, M.D., Ph.D.; Shaun Gallagher, Ph.D.; Kenneth S. Kendler, M.D.; Sandra D. Mitchell, Ph.D.; Dominic P. Murphy, Ph.D.; Josef Parnas, M.D., Dr.Med.Sci.; Louis A. Sass, Ph.D.; Kenneth F. Schaffner, M.D., Ph.D.; James F. Woodward, Ph.D.; Peter Zachar, Ph.D. (shrink)

IN Being and Time and elsewhere M. Heidegger asserts that there is no truth prior to the "discovering being" of man. According to this view, the truth of the Newtonian laws, for example, would have existed only since and through Newton's discoveries. Heidegger only spells out the logical consequences of this position when he asserts that the suicide extinguishes not only his "being-there," but also the truth.